Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts
Across TCGA cell cohorts, KRTAP21-1 mutation is significantly associated with the RNA expression of many other genes, with 176 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.
The most reproducible KRTAP21-1-associated genes across cancer lineages are UBE2U, ACTR3B, and THEM4. Each is linked with KRTAP21-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP21-1-to-partner and partner-to-KRTAP21-1 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (KRTAP21-1→partner) and Y-score (partner→KRTAP21-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.