KRTAP19-3

Across TCGA cell cohorts, KRTAP19-3 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KRTAP19-3-associated genes across cancer lineages are LUZP4, ZP2, and FATE1. Each is linked with KRTAP19-3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP19-3-to-partner and partner-to-KRTAP19-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LUZP4 grouped by KRTAP19-3-low versus KRTAP19-3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP19-3→partner) and Y-score (partner→KRTAP19-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LUZP4 →	+0.569	+5.060	<.001	.001	3	1
BLOOD_Leukemia	ZP2 →	+0.153	+4.409	<.001	.005	3	1
BLOOD_Leukemia	FATE1 →	+0.137	+4.551	<.001	.004	3	1
BLOOD_Leukemia	TMEM244 →	+0.343	+4.551	<.001	.004	3	1
BLOOD_Leukemia	PAGE3 →	+0.082	+4.969	<.001	.003	3	1
BLOOD_Leukemia	TEX13A →	+0.047	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

LUZP4 by KRTAP19-3 expression — BLOOD_Leukemia

Explore this box plot interactively →