Across TCGA patient cohorts, KRTAP19-2 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP19-2-associated genes across cancer lineages are MTCO1P44, RNU6-1258P, and AKR1B10P2. Each is linked with KRTAP19-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP19-2-to-partner and partner-to-KRTAP19-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP19-2→partner) and Y-score (partner→KRTAP19-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MTCO1P44 →	+0.174	+7.930	<.001	.008	3	1
LUAD	RNU6-1258P →	+0.443	+7.930	<.001	.008	3	1
UCEC	AKR1B10P2 →	+0.107	+5.358	<.001	.006	3	1
UCEC	RNU6-380P →	+0.710	+7.470	<.001	<.001	3	1
UCEC	RNA5SP113 →	+2.417	+6.226	<.001	.001	3	1
UCEC	NEK4P1 →	+0.098	+6.123	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

KRTAP19-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP19-2 data types