KRTAP12-1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP12-1 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP12-1-associated genes across cancer lineages are MED28P1, RNU6-875P, and KNOP1P3. Each is linked with KRTAP12-1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP12-1-to-partner and partner-to-KRTAP12-1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP12-1→partner) and Y-score (partner→KRTAP12-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMED28P1 →+0.356+4.201<.001<.00132
UCECRNU6-875P →+0.554+2.592.008.00932
LUSCKNOP1P3 →+0.213+5.882<.001.00232
SKCMOR1AC1P →+0.354+2.668.001.00932
SKCMLIN28B-AS1 →+0.303+3.357.001<.00132
SKCMMIR26A2 →+0.604+3.666.009.00332
Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

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