LIN28B-AS1

Q-omics provides the consensus-scored LIN28B-AS1 profile across patient tissues and cancer cell-line models. LIN28B-AS1 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in KIRP. Additionally, LIN28B-AS1 RNA expression shows 12,503 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight KIRP, and TGCT as cancer lineages where LIN28B-AS1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes LIN28B-AS1 survival associations across molecular data types. LIN28B-AS1 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

LIN28B-AS1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	14	KIRP (63)	view →

This table ranks reproducible LIN28B-AS1 RNA expression–survival associations across cancer types. High LIN28B-AS1 expression shows unfavorable associations in KIRP, MESO, LUSC and KIRC, but favorable associations in UCS and UVM. The KIRP Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KIRP as the clearest survival context for LIN28B-AS1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Tertile	II,III,IV	0.127	0.713	.001	63	view →
MESO	DFS	Tertile	III,IV	0.082	0.414	.007	54	view →
UCS	DFS	Tertile	II,III,IV	0.658	0.225	.001	44	view →
UVM	DFS	Tertile	All	0.961	0.662	.013	37	view →
LUSC	OS	Tertile	III,IV	0.242	0.684	.006	36	view →
KIRC	DFS	Tertile	III,IV	0.442	0.760	.023	36	view →

Pink = unfavorable, green = favorable. all 14 lineages →

LIN28B-AS1-KIRP (DFS)

Explore this curve interactively →