Across TCGA cell cohorts, KRTAP10-9 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible KRTAP10-9-associated genes across cancer lineages are ACTRT1, TGM7, and KRTAP4-5. Each is linked with KRTAP10-9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-9-to-partner and partner-to-KRTAP10-9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-9→partner) and Y-score (partner→KRTAP10-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ACTRT1 →	+0.015	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	TGM7 →	+0.006	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	KRTAP4-5 →	+0.022	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	SPATA31D1 →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	C1orf232 →	+0.030	+4.887	.002	.009	3	1
LARGE_INTESTINE	MROH2B →	+0.006	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

KRTAP10-9 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-9 data types