Across TCGA pan-cancer cohorts, KRTAP10-9 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated KRTAP10-9 data layer compared with 2 for mutation status.
The strongest signal is observed in breast invasive carcinoma (BRCA), where higher KRTAP10-9 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRTAP10-9 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.
BRCA, UVM, and CHOL are the cancer types where KRTAP10-9 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.