KRTAP10-7

Across TCGA patient cohorts, KRTAP10-7 mutation is significantly associated with the RNA expression of many other genes, with 1,733 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-7-associated genes across cancer lineages are ZNRF3, TANGO2, and LONP1. Each is linked with KRTAP10-7 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-7-to-partner and partner-to-KRTAP10-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNRF3 grouped by KRTAP10-7-low versus KRTAP10-7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-7→partner) and Y-score (partner→KRTAP10-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNRF3 →	+0.259	+3.377	<.001	.004	3	2
UCEC	TANGO2 →	+0.599	+3.818	<.001	<.001	3	2
UCEC	LONP1 →	+0.835	+3.616	<.001	.001	3	2
UCEC	NCKIPSD →	+0.568	+3.191	<.001	.009	3	2
UCEC	SLC35F6 →	+0.554	+3.210	<.001	.009	3	2
UCEC	ZDHHC7 →	+0.643	+3.807	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,733 associations by consensus.

ZNRF3 by KRTAP10-7 expression — UCEC

Explore this box plot interactively →