Across TCGA patient cohorts, KRTAP10-6 mutation is significantly associated with the RNA expression of many other genes, with 216 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-6-associated genes across cancer lineages are ADAM20P2, TRGV1, and NANOGP10. Each is linked with KRTAP10-6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-6-to-partner and partner-to-KRTAP10-6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-6→partner) and Y-score (partner→KRTAP10-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	ADAM20P2 →	+0.034	+6.632	<.001	<.001	3	2
COAD	TRGV1 →	+0.224	+4.681	<.001	.003	3	2
COAD	NANOGP10 →	+0.125	+5.251	<.001	.003	3	2
BLCA	TRAJ21 →	+0.990	+4.497	<.001	.009	3	2
LUSC	RNA5SP45 →	+0.265	+4.906	<.001	.003	3	2
SKCM	RNU6-1169P →	+0.223	+3.625	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 216 associations by consensus.

Exploration

KRTAP10-6 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-6 data types