KRTAP10-6

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KRTAP10-6 mutation is significantly associated with the total protein of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-6-associated genes across cancer lineages are C-Raf, STAT3_pY705, and AR. Each is linked with KRTAP10-6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-6-to-partner and partner-to-KRTAP10-6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-6→partner) and Y-score (partner→KRTAP10-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECC-Raf →+0.248+3.000.002.03732
UCECSTAT3_pY705 →-0.400-3.000.008.03731
UCECAR →-0.571-3.000.008.03731
UCECTuberin →+0.377+3.000.015.03731
UCECCaspase-8 →-0.302-3.000.037.03722
UCECChk2 →-0.311-3.000.021.03731
Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration