Across TCGA patient cohorts, KRTAP10-2 mutation is significantly associated with the RNA expression of many other genes, with 95 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRTAP10-2-associated genes across cancer lineages are SSX7, MIR4422, and OR51A7. Each is linked with KRTAP10-2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRTAP10-2-to-partner and partner-to-KRTAP10-2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRTAP10-2→partner) and Y-score (partner→KRTAP10-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SSX7 →	+0.171	+4.290	<.001	<.001	3	2
UCEC	MIR4422 →	+0.737	+4.420	<.001	<.001	3	2
UCEC	OR51A7 →	+0.123	+3.021	.004	.006	3	1
COAD	RNU6-340P →	+0.353	+7.741	<.001	.009	3	1
COAD	TRBV22OR9-2 →	+0.289	+7.741	<.001	.009	3	1
UCEC	NUTF2P8 →	+0.148	+3.246	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

Exploration

KRTAP10-2 survival (RNA) · tumor vs normal (RNA) · all KRTAP10-2 data types