KRT86

Across TCGA patient cohorts, KRT86 mutation is significantly associated with the RNA expression of many other genes, with 199 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible KRT86-associated genes across cancer lineages are RNU6-452P, RNU6-90P, and FAM8A4P. Each is linked with KRT86 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT86-to-partner and partner-to-KRT86 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-452P grouped by KRT86-low versus KRT86-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT86→partner) and Y-score (partner→KRT86) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-452P →	+0.373	+4.423	<.001	.007	3	3
UCEC	RNU6-90P →	+0.598	+3.249	.006	.005	3	3
LIHC	FAM8A4P →	+0.039	+4.547	<.001	.001	3	2
LIHC	OR7E117P →	+0.025	+4.720	.003	.005	3	2
LGG	PRM3 →	+0.081	+4.529	<.001	.009	3	2
LGG	SNRPEP7 →	+0.200	+4.977	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 199 associations by consensus.

RNU6-452P by KRT86 expression — LIHC

Explore this box plot interactively →