KRT85

Across TCGA patient cohorts, KRT85 mutation is significantly associated with the RNA expression of many other genes, with 2,130 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT85-associated genes across cancer lineages are MIR4308, REEP5, and AOC2. Each is linked with KRT85 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT85-to-partner and partner-to-KRT85 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4308 grouped by KRT85-low versus KRT85-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT85→partner) and Y-score (partner→KRT85) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MIR4308 →	+0.604	+4.114	<.001	<.001	3	3
COAD	REEP5 →	+0.418	+3.486	.001	.002	3	3
UCEC	AOC2 →	+0.742	+2.078	<.001	<.001	3	3
UCEC	TYMS →	+0.615	+2.115	.003	<.001	3	3
UCEC	TIMM22 →	+0.327	+2.162	.001	.002	3	3
COAD	RPL17P50 →	+1.010	+3.361	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,130 associations by consensus.

MIR4308 by KRT85 expression — LUAD

Explore this box plot interactively →