Q-omics provides the consensus-scored MIR4308 profile across patient tissues and cancer cell-line models. MIR4308 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, MIR4308 is differentially expressed in 1, with the highest sampling consensus in KICH. Additionally, MIR4308 RNA expression shows 6,153 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KIRC, KICH, and STAD as cancer lineages where MIR4308 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for MIR4308 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes MIR4308 survival associations across molecular data types. MIR4308 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible MIR4308 RNA expression–survival associations across cancer types. High MIR4308 expression shows unfavorable associations in KIRC, DLBC and LUSC, but favorable associations in STAD, OV and UCEC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify KIRC as the clearest survival context for MIR4308 RNA expression.
This table summarizes MIR4308 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for MIR4308. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. MIR4308 shows lower tumor expression in KICH. The KICH box plot shows higher MIR4308 RNA expression in normal versus tumor tissue (log2 FC = −0.477, t-test p = .025).
This table shows molecular features associated with MIR4308 in patient tissues and cancer cell lines. In patient samples, MIR4308 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
