KRT85

Across TCGA pan-cancer cohorts, KRT85 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated KRT85 data layer compared with 6 for mutation status and 1 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher KRT85 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KRT85 expression acts as an unfavorable survival marker, although some lineages such as ESCA and THCA show a favorable association.

KICH, STAD, and BLCA are the cancer types where KRT85 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.043	0.971	<.001	54	view →
STAD	DFS	Quartile	IV	0.153	0.575	<.001	54	view →
BLCA	OS	Quartile	IV	0.289	0.557	.001	51	view →
ESCA	OS	Quartile	III,IV	0.714	0.368	.004	37	view →
THCA	DFS	Quartile	All	0.942	0.784	.006	26	view →
GBM	OS	Tertile	All	0.284	0.470	.020	15	view →
LUAD	DFS	Quartile	III,IV	0.192	0.477	.022	14	view →
KIRP	DFS	Tertile	All	0.391	0.900	.002	12	view →
CHOL	OS	Tertile	II,III,IV	0.080	0.740	.038	12	view →
SKCM	OS	Quartile	III,IV	0.914	0.749	.012	10	view →
HNSC	OS	Tertile	II,III,IV	0.468	0.259	.018	9	view →
PCPG	OS	Tertile	All	0.786	0.963	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

KRT85–KICH (DFS)

Open the KICH breakdown →