KRT78

Across TCGA patient cohorts, KRT78 mutation is significantly associated with the RNA expression of many other genes, with 988 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT78-associated genes across cancer lineages are RNA5SP427, MIR4511, and RAMP1. Each is linked with KRT78 in more than 2 cancer types. Because this analysis shows association rather than direction, both KRT78-to-partner and partner-to-KRT78 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP427 grouped by KRT78-low versus KRT78-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT78→partner) and Y-score (partner→KRT78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RNA5SP427 →	+0.156	+4.314	<.001	.009	3	3
BLCA	MIR4511 →	+0.347	+4.266	<.001	.003	3	2
SKCM	RAMP1 →	-1.577	-2.302	<.001	.001	3	2
UCEC	TMEM120B →	+0.413	+3.218	.003	.009	3	2
UCEC	NFYBP1 →	+0.169	+2.086	.004	.003	3	2
COAD	PTP4A1P7 →	+0.393	+3.880	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 988 associations by consensus.

RNA5SP427 by KRT78 expression — BLCA

Explore this box plot interactively →