Across TCGA patient cohorts, KRT25 protein abundance is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KRT25-associated genes across cancer lineages are SEC23A, TUBD1, and KHDRBS2. Each is linked with KRT25 in more than 1 cancer types. Because this analysis shows association rather than direction, both KRT25-to-partner and partner-to-KRT25 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT25→partner) and Y-score (partner→KRT25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEC23A →	-0.529	-0.454	.003	.005	2	1
HNSC	TUBD1 →	+0.254	+0.489	.001	.001	2	1
HNSC	KHDRBS2 →	-0.330	-0.454	.009	.005	2	1
HNSC	TEX14 →	-0.464	-0.459	.006	.006	2	1
HNSC	VPREB3 →	-1.989	-0.454	.009	.005	2	1
HNSC	LLPH →	-0.319	-0.454	.006	.005	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

KRT25 survival (RNA) · tumor vs normal (RNA) · all KRT25 data types