KRT18P54

Across TCGA patient cohorts, KRT18P54 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,889 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KRT18P54-associated GO terms across cancer lineages are DNA protection, Sarcomere organization, and Methylglyoxal metabolic process. Each is linked with KRT18P54 in more than 6 cancer types. Because this analysis shows association rather than direction, both KRT18P54-to-partner and partner-to-KRT18P54 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA protection grouped by KRT18P54-low versus KRT18P54-high in HNSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KRT18P54→partner) and Y-score (partner→KRT18P54) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	DNA protection →	+0.038	+0.027	<.001	<.001	2	7
ESCA	Sarcomere organization →	+0.055	+0.246	<.001	<.001	3	5
CHOL	Methylglyoxal metabolic process →	+0.045	+0.053	.005	.005	2	6
READ	Pyrimidine ribonucleoside triphosphate biosynthetic process →	+0.025	+0.194	<.001	.005	2	6
COAD	Pyrimidine ribonucleotide biosynthetic process →	+0.018	+0.139	<.001	<.001	3	5
READ	UTP biosynthetic process →	+0.040	+0.260	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,889 associations by consensus.

DNA protection by KRT18P54 expression — HNSC

Explore this box plot interactively →