KRT18P54

Across TCGA pan-cancer cohorts, KRT18P54 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated KRT18P54 data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher KRT18P54 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KRT18P54 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUSC show a favorable association.

OV, PAAD, and UVM are the cancer types where KRT18P54 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	All	0.634	0.741	<.001	100	view →
PAAD	DFS	Tertile	All	0.176	0.319	.004	84	view →
UVM	OS	Tertile	II,III,IV	0.218	0.718	.006	72	view →
BRCA	OS	Median	IV	0.324	0.676	.017	55	view →
LUAD	OS	Tertile	All	0.148	0.409	<.001	54	view →
CHOL	DFS	Tertile	All	0.097	0.529	<.001	36	view →
MESO	OS	Tertile	All	0.281	0.439	.002	35	view →
ESCA	OS	Quartile	All	0.396	0.688	.001	32	view →
UCS	OS	Tertile	IV	0.269	0.624	.042	18	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
THCA	OS	Tertile	All	0.838	0.982	.003	12	view →
COAD	OS	Quartile	All	0.743	0.526	.017	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

KRT18P54–OV (OS)

Open the OV breakdown →