KRT18P54

Across TCGA pan-cancer cohorts, KRT18P54 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of KRT18P54’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where KRT18P54 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KRT18P54 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

STAD, COAD, and THCA are the cancer types where KRT18P54 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KRT18P54 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.500	<.001	7	view →
COAD	All	II,III,IV	+0.091	.027	2	view →
THCA	Female	II,III,IV	+0.045	.040	2	view →
BRCA	All	All	+0.021	.049	2	view →
LUAD	All	III,IV	+0.102	.027	1	view →
CHOL	All	All	+0.051	.024	1	view →
LUSC	All	II,III,IV	+0.033	.042	1	view →
KICH	All	II,III,IV	−0.025	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

KRT18P54–STAD

Open the STAD breakdown →