KPNA5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KPNA5 mutation is significantly associated with the RNA expression of many other genes, with 567 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KPNA5-associated genes across cancer lineages are LINC00428, RNU6-763P, and RPL31P9. Each is linked with KPNA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both KPNA5-to-partner and partner-to-KPNA5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA5→partner) and Y-score (partner→KPNA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCLINC00428 →+0.232+5.306<.001.00633
PRADRNU6-763P →+0.643+7.939<.001.00832
COADRPL31P9 →+0.522+5.721<.001.00132
LUADAPOOP2 →+0.284+4.990<.001.00932
UCECMTHFD2P3 →+0.127+2.304.004.00532
UCECRNA5SP410 →+0.444+1.895.005.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 567 associations by consensus.

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