KPNA1

Across TCGA patient cohorts, KPNA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,615 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KPNA1-associated proteins across cancer lineages are FXR1, ZNF148, and NCK1. Each is linked with KPNA1 in more than 5 cancer types. Because this analysis shows association rather than direction, both KPNA1-to-partner and partner-to-KPNA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KPNA1 versus FXR1 in LSCC, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KPNA1→partner) and Y-score (partner→KPNA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FXR1 →	+0.397	+0.646	<.001	<.001	3	6
LSCC	ZNF148 →	+0.319	+0.681	<.001	<.001	3	6
PDAC	NCK1 →	+0.258	+0.199	<.001	.007	3	5
LSCC	TOPBP1 →	+0.467	+0.611	<.001	<.001	3	5
LSCC	UMPS →	+0.458	+0.699	<.001	<.001	3	5
LSCC	DCUN1D1 →	+0.322	+0.509	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,615 associations by consensus.

KPNA1 vs FXR1 — LSCC

Explore this scatter interactively →