KNG1

Across TCGA patient cohorts, KNG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,018 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KNG1-associated GO terms across cancer lineages are Aerobic respiration, Nucleoside phosphate biosynthetic process, and Mitochondrial fusion. Each is linked with KNG1 in more than 14 cancer types. Because this analysis shows association rather than direction, both KNG1-to-partner and partner-to-KNG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by KNG1-low versus KNG1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KNG1→partner) and Y-score (partner→KNG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Aerobic respiration →	+0.069	+0.468	<.001	.002	3	15
ESCA	Nucleoside phosphate biosynthetic process →	+0.075	+0.547	<.001	.002	3	14
STAD	Mitochondrial fusion →	+0.059	+0.340	<.001	<.001	3	13
STAD	Nucleoside monophosphate biosynthetic process →	+0.054	+0.234	<.001	<.001	3	13
STAD	Protein localization to mitochondrion →	+0.059	+0.333	<.001	<.001	3	13
ESCA	Regulation of transcription by RNA polymerase I →	+0.094	+0.661	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,018 associations by consensus.

Aerobic respiration by KNG1 expression — ESCA

Explore this box plot interactively →