KNG1

Across TCGA pan-cancer cohorts, KNG1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated KNG1 data layer compared with 6 for mutation status and 8 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher KNG1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated KNG1 expression acts as an unfavorable survival marker, although some lineages such as LIHC and READ show a favorable association.

LIHC, READ, and KIRP are the cancer types where KNG1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	All	0.594	0.429	<.001	75	view →
READ	DFS	Median	III,IV	0.905	0.580	<.001	52	view →
KIRP	OS	Tertile	All	0.651	0.854	.002	38	view →
LGG	OS	Tertile	All	0.842	0.940	<.001	36	view →
CHOL	OS	Tertile	II,III,IV	0.231	0.919	.002	28	view →
COAD	DFS	Median	III,IV	0.529	0.762	.002	25	view →
LUAD	DFS	Tertile	III,IV	0.422	0.738	.007	24	view →
PAAD	DFS	Tertile	II,III,IV	0.563	0.321	.006	24	view →
KIRC	DFS	Median	III,IV	0.572	0.701	.014	23	view →
ESCA	OS	Median	All	0.617	1.000	.009	15	view →
STAD	DFS	Median	All	0.323	0.461	.019	14	view →
ACC	DFS	Tertile	II,III,IV	0.713	0.282	.028	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

KNG1–LIHC (DFS)

Open the LIHC breakdown →