KMT5C

Across TCGA patient cohorts, KMT5C protein abundance is significantly associated with the RNA expression of many other genes, with 2,433 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KMT5C-associated genes across cancer lineages are IGFLR1, MIR4324, and IGHD4-23. Each is linked with KMT5C in more than 1 cancer types. Because this analysis shows association rather than direction, both KMT5C-to-partner and partner-to-KMT5C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KMT5C versus IGFLR1 in HNSC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KMT5C→partner) and Y-score (partner→KMT5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	IGFLR1 →	+0.637	+0.744	<.001	<.001	3	2
HNSC	MIR4324 →	+2.183	+0.692	.001	<.001	3	2
LUAD	IGHD4-23 →	-1.638	-0.842	.001	.002	3	2
BRCA	NAT14 →	+0.673	+0.630	.008	.002	3	2
UCEC	NALCN →	-0.631	-0.613	.006	.002	3	2
LUAD	RAB29 →	-0.702	-0.925	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,433 associations by consensus.

KMT5C vs IGFLR1 — HNSC

Explore this scatter interactively →