KMT2C

Across TCGA patient cohorts, KMT2C RNA expression is significantly associated with the protein abundance of many other proteins, with 14,040 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KMT2C-associated proteins across cancer lineages are PRDM1_S272, GTF2I, and KMT2C_S4034. Each is linked with KMT2C in more than 5 cancer types. Because this analysis shows association rather than direction, both KMT2C-to-partner and partner-to-KMT2C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KMT2C versus PRDM1_S272 in LUAD, with a Pearson correlation of -0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KMT2C→partner) and Y-score (partner→KMT2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PRDM1_S272 →	-0.937	-0.444	<.001	<.001	3	5
GBM	GTF2I →	+0.427	+0.498	<.001	<.001	3	5
HNSC	KMT2C_S4034 →	+0.438	+0.459	<.001	<.001	2	6
OV	RPL26 →	-0.611	-1.184	.003	.005	3	5
LSCC	SF3B3 →	+0.235	+0.375	<.001	.002	3	5
GBM	STAG2 →	+0.269	+0.380	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,040 associations by consensus.

KMT2C vs PRDM1_S272 — LUAD

Explore this scatter interactively →