KLK15

Across TCGA cell cohorts, KLK15 RNA expression is significantly associated with the go_rna of many other GO terms, with 667 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLK15-associated GO terms across cancer lineages are Regulation of AV node cell action potential, Negative regulation of beige fat cell differentiation, and Negative regulation of cyclin-dependent protein kinase activity. Each is linked with KLK15 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLK15-to-partner and partner-to-KLK15 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of AV node cell action potential grouped by KLK15-low versus KLK15-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLK15→partner) and Y-score (partner→KLK15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of AV node cell action potential →	+0.970	+0.027	.002	.006	3	4
LARGE_INTESTINE	Negative regulation of beige fat cell differentiation →	-0.092	-0.510	<.001	.007	3	3
LARGE_INTESTINE	Negative regulation of cyclin-dependent protein kinase activity →	-0.100	-0.737	<.001	<.001	3	3
LARGE_INTESTINE	Negative regulation of cyclin-dependent protein serine/threonine kinase activity →	-0.100	-0.737	<.001	<.001	3	3
LARGE_INTESTINE	Regulation of mesonephros development →	-0.986	-0.758	<.001	<.001	3	3
LARGE_INTESTINE	Acyl-CoA metabolic process →	+0.075	+0.688	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 667 associations by consensus.

Regulation of AV node cell action potential by KLK15 expression — SOFT_TISSUE

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