KLHL7-DT

Across TCGA patient cohorts, KLHL7-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 7,631 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL7-DT-associated proteins across cancer lineages are MSH2, MSH6, and HEATR1. Each is linked with KLHL7-DT in more than 4 cancer types. Because this analysis shows association rather than direction, both KLHL7-DT-to-partner and partner-to-KLHL7-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL7-DT versus MSH2 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL7-DT→partner) and Y-score (partner→KLHL7-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MSH2 →	+0.396	+0.413	<.001	<.001	3	5
OV	MSH6 →	+0.468	+0.767	<.001	<.001	3	5
LSCC	HEATR1 →	+0.280	+0.448	.002	.004	3	5
LSCC	MPHOSPH10 →	+0.311	+0.462	.002	.003	3	4
LSCC	NOC2L →	+0.319	+0.514	.001	.001	3	4
GBM	SP4 →	+0.479	+0.524	.009	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,631 associations by consensus.

KLHL7-DT vs MSH2 — LSCC

Explore this scatter interactively →