KLHL41

Across TCGA patient cohorts, KLHL41 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,004 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KLHL41-associated proteins across cancer lineages are APPL1, PURA, and EIF4G1. Each is linked with KLHL41 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLHL41-to-partner and partner-to-KLHL41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL41 versus APPL1 in BRCA, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL41→partner) and Y-score (partner→KLHL41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	APPL1 →	+0.278	+0.428	<.001	.002	3	5
BRCA	PURA →	+0.466	+0.496	<.001	<.001	3	5
HNSC	EIF4G1 →	-0.227	-2.150	<.001	<.001	3	5
BRCA	KANK2 →	+0.571	+0.448	<.001	<.001	3	5
UCEC	MAPRE3 →	+0.524	+0.517	<.001	<.001	3	5
BRCA	RPL10 →	-0.356	-0.507	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,004 associations by consensus.

KLHL41 vs APPL1 — BRCA

Explore this scatter interactively →