KLHL41

Across TCGA patient cohorts, KLHL41 protein abundance is significantly associated with the RNA expression of many other genes, with 1,911 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KLHL41-associated genes across cancer lineages are MUC4, PRRX2, and SLC52A3. Each is linked with KLHL41 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL41-to-partner and partner-to-KLHL41 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL41 versus MUC4 in LSCC, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL41→partner) and Y-score (partner→KLHL41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MUC4 →	-1.867	-0.304	<.001	.002	3	2
LSCC	PRRX2 →	-1.601	-0.571	<.001	.006	3	2
LSCC	SLC52A3 →	-0.939	-0.391	.001	.002	3	1
LSCC	MAP1LC3A →	-0.955	-0.439	.001	.006	3	1
LSCC	SLC1A5 →	-1.135	-0.338	.001	.001	3	1
LSCC	CEACAM5 →	-2.531	-0.384	.008	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,911 associations by consensus.

KLHL41 vs MUC4 — LSCC

Explore this scatter interactively →