KLHL41

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KLHL41 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,143 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible KLHL41-associated GO terms across cancer lineages are Intraciliary transport, Transport along microtubule, and Regulation of RNA splicing. Each is linked with KLHL41 in more than 8 cancer types. Because this analysis shows association rather than direction, both KLHL41-to-partner and partner-to-KLHL41 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary transport grouped by KLHL41-low versus KLHL41-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL41→partner) and Y-score (partner→KLHL41) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTIntraciliary transport →+0.064+0.305.001.00139
STOMACHTransport along microtubule →+0.045+0.290.001.00238
SOFT_TISSUERegulation of RNA splicing →+0.074+3.012.001.00238
STOMACHMicrotubule-based transport →+0.032+0.277.002.00337
SOFT_TISSUEVascular process in circulatory system →-0.051-2.680<.001.00237
LUNG_NSCLC_LUADLymphocyte chemotaxis →-0.164-0.210<.001.00637
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,143 associations by consensus.

Intraciliary transport by KLHL41 expression — BREAST

Box plot of Intraciliary transport in KLHL41-low vs KLHL41-high samples in BREAST.

Explore this box plot interactively →

Exploration