KLHL33

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, KLHL33 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLHL33-associated genes across cancer lineages are FMR1NB, PTH2R, and DEUP1. Each is linked with KLHL33 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL33-to-partner and partner-to-KLHL33 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL33→partner) and Y-score (partner→KLHL33) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEFMR1NB →+0.231+3.453<.001.00931
LARGE_INTESTINEPTH2R →+1.125+3.453<.001.00921
LARGE_INTESTINEDEUP1 →+0.456+3.569<.001.00621
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

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