KLHL31

Across TCGA patient cohorts, KLHL31 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,565 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL31-associated proteins across cancer lineages are GCLC, ACOT13, and COQ7. Each is linked with KLHL31 in more than 4 cancer types. Because this analysis shows association rather than direction, both KLHL31-to-partner and partner-to-KLHL31 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL31 versus GCLC in LSCC, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL31→partner) and Y-score (partner→KLHL31) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GCLC →	+1.327	+0.955	<.001	<.001	3	5
HNSC	ACOT13 →	+0.359	+0.883	<.001	<.001	3	4
BRCA	COQ7 →	+0.356	+0.491	.001	<.001	3	4
LSCC	HTRA2 →	+0.296	+0.523	<.001	.003	3	4
LSCC	GMPPB →	-0.505	-0.895	<.001	<.001	3	4
OV	GSDMD →	-0.350	-0.637	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,565 associations by consensus.

KLHL31 vs GCLC — LSCC

Explore this scatter interactively →