KLHL29

Across TCGA patient cohorts, KLHL29 protein abundance is significantly associated with the protein abundance of many other proteins, with 10,879 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KLHL29-associated proteins across cancer lineages are TRIM28_S697, URB2, and MGST1. Each is linked with KLHL29 in more than 3 cancer types. Because this analysis shows association rather than direction, both KLHL29-to-partner and partner-to-KLHL29 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL29 versus TRIM28_S697 in HNSC, with a Pearson correlation of 0.49.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL29→partner) and Y-score (partner→KLHL29) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRIM28_S697 →	+0.934	+0.900	<.001	<.001	3	3
PDAC	URB2 →	+0.331	+0.466	.003	<.001	2	4
GBM	MGST1 →	-1.018	-0.647	<.001	<.001	3	3
PDAC	ORC5 →	+0.730	+0.507	<.001	.002	2	4
UCEC	PALM2AKAP2 →	+0.407	+0.509	<.001	<.001	3	3
HNSC	GABPB1 →	+0.342	+0.703	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,879 associations by consensus.

KLHL29 vs TRIM28_S697 — HNSC

Explore this scatter interactively →