KLHL24

Across TCGA patient cohorts, KLHL24 protein abundance is significantly associated with the RNA expression of many other genes, with 1,947 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLHL24-associated genes across cancer lineages are SLC25A5, MTND5P15, and LIPA. Each is linked with KLHL24 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL24-to-partner and partner-to-KLHL24 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLHL24 versus SLC25A5 in OV, with a Pearson correlation of -0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL24→partner) and Y-score (partner→KLHL24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SLC25A5 →	-0.893	-0.868	.002	<.001	3	2
LUAD	MTND5P15 →	+0.525	+0.269	.005	.005	3	2
UCEC	LIPA →	-1.055	-0.509	<.001	<.001	3	1
UCEC	PSMG2 →	-0.480	-0.314	.002	.006	3	1
UCEC	DRAM1 →	-1.167	-0.478	.002	.004	3	1
UCEC	PARN →	-0.353	-0.433	.007	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,947 associations by consensus.

KLHL24 vs SLC25A5 — OV

Explore this scatter interactively →