KLHL24

Across TCGA cell cohorts, KLHL24 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,245 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLHL24-associated GO terms across cancer lineages are Regulation of vacuole organization, Thymidine biosynthetic process, and 2'-deoxyribonucleoside biosynthetic process. Each is linked with KLHL24 in more than 16 cancer types. Because this analysis shows association rather than direction, both KLHL24-to-partner and partner-to-KLHL24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of vacuole organization grouped by KLHL24-low versus KLHL24-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL24→partner) and Y-score (partner→KLHL24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of vacuole organization →	+0.063	+1.519	<.001	<.001	3	17
OESOPHAGUS	Thymidine biosynthetic process →	-0.256	-2.768	<.001	<.001	3	17
OESOPHAGUS	2'-deoxyribonucleoside biosynthetic process →	-0.256	-2.768	<.001	<.001	3	17
OESOPHAGUS	Pyrimidine deoxyribonucleoside biosynthetic process →	-0.256	-2.768	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Negative regulation of macroautophagy →	+0.076	+1.029	<.001	.006	3	16
OESOPHAGUS	Regulation of autophagosome assembly →	+0.080	+1.619	<.001	.002	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,245 associations by consensus.

Regulation of vacuole organization by KLHL24 expression — OVARY

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