KLHL24

Across TCGA cell cohorts, KLHL24 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KLHL24-associated genes across cancer lineages are KLHL40, LYPD4, and C5orf52. Each is linked with KLHL24 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLHL24-to-partner and partner-to-KLHL24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KLHL40 grouped by KLHL24-low versus KLHL24-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLHL24→partner) and Y-score (partner→KLHL24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KLHL40 →	+0.006	+5.209	.006	.005	3	2
LARGE_INTESTINE	LYPD4 →	+0.051	+3.920	.004	.005	3	1
SKIN	C5orf52 →	+0.030	+4.415	<.001	.007	3	1
SKIN	SPINK9 →	+0.043	+4.415	<.001	.007	3	1
BLOOD_Lymphoma	OR2AJ1 →	+0.042	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR6J1 →	+0.006	+5.643	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

KLHL40 by KLHL24 expression — BLOOD_Lymphoma

Explore this box plot interactively →