KLF9

Across TCGA patient cohorts, KLF9 mutation is significantly associated with the RNA expression of many other genes, with 4,482 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLF9-associated genes across cancer lineages are MTND6P16, RNU1-4, and NFYBP1. Each is linked with KLF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF9-to-partner and partner-to-KLF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND6P16 grouped by KLF9-low versus KLF9-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF9→partner) and Y-score (partner→KLF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MTND6P16 →	+0.056	+5.837	<.001	.001	3	2
CESC	RNU1-4 →	+0.175	+5.837	<.001	.001	3	2
UCEC	NFYBP1 →	+0.168	+1.671	<.001	.003	3	2
UCEC	EZH2P1 →	+0.268	+1.666	<.001	.001	3	2
UCEC	LINC01072 →	+0.098	+2.096	<.001	.001	3	2
CESC	TULP3P1 →	+0.095	+4.320	.003	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,482 associations by consensus.

MTND6P16 by KLF9 expression — CESC

Explore this box plot interactively →