KLF7-IT1

Across TCGA patient cohorts, KLF7-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,589 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KLF7-IT1-associated proteins across cancer lineages are COL5A1, ACTBL2, and MRPL22. Each is linked with KLF7-IT1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KLF7-IT1-to-partner and partner-to-KLF7-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLF7-IT1 versus COL5A1 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF7-IT1→partner) and Y-score (partner→KLF7-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COL5A1 →	+0.642	+0.473	.005	.003	3	5
PDAC	ACTBL2 →	+0.259	+0.377	.002	.001	3	4
UCEC	MRPL22 →	-0.325	-0.659	<.001	<.001	3	4
PDAC	TMOD3 →	+0.197	+0.456	.005	.001	3	4
PDAC	PREB →	-0.260	-0.442	.001	.004	2	5
LSCC	SERPINE1 →	+1.137	+0.727	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,589 associations by consensus.

KLF7-IT1 vs COL5A1 — BRCA

Explore this scatter interactively →