KLF17

Across TCGA patient cohorts, KLF17 mutation is significantly associated with the RNA expression of many other genes, with 2,756 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLF17-associated genes across cancer lineages are RAD51C, CCDC47, and PPCS. Each is linked with KLF17 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLF17-to-partner and partner-to-KLF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAD51C grouped by KLF17-low versus KLF17-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF17→partner) and Y-score (partner→KLF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RAD51C →	+0.393	+2.141	.007	.009	3	3
SKCM	CCDC47 →	+0.647	+2.434	.001	.001	3	3
SKCM	PPCS →	+0.433	+2.623	.003	.005	3	3
UCEC	ARFGAP3 →	+0.800	+2.545	<.001	.001	3	3
UCEC	CCDC86 →	+0.578	+3.512	.001	.002	3	3
SKCM	SRRD →	+0.485	+2.522	.003	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,756 associations by consensus.

RAD51C by KLF17 expression — SKCM

Explore this box plot interactively →