KLF17

Across TCGA pan-cancer cohorts, KLF17 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated KLF17 data layer compared with 3 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher KLF17 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated KLF17 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCS show a favorable association.

KIRC, CESC, and COAD are the cancer types where KLF17 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.529	0.692	<.001	114	view →
CESC	DFS	Tertile	All	0.733	0.850	.005	48	view →
COAD	DFS	Median	All	0.350	0.617	<.001	48	view →
LGG	OS	Median	All	0.845	0.942	<.001	44	view →
LUSC	DFS	Median	II,III,IV	0.309	0.469	.013	37	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	36	view →
ACC	DFS	Tertile	All	0.447	0.887	.002	26	view →
HNSC	DFS	Tertile	IV	0.553	0.277	.002	25	view →
UCS	DFS	Median	IV	0.909	0.416	.008	24	view →
BLCA	DFS	Median	All	0.283	0.420	.007	21	view →
READ	DFS	Median	III,IV	0.352	0.711	.007	14	view →
UCEC	OS	Quartile	III,IV	0.741	0.895	.028	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

KLF17–KIRC (OS)

Open the KIRC breakdown →