KLF17

Across TCGA cell cohorts, KLF17 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,131 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KLF17-associated GO terms across cancer lineages are Regulation of focal adhesion assembly, Regulation of cell-substrate junction assembly, and Positive regulation of actin filament bundle assembly. Each is linked with KLF17 in more than 10 cancer types. Because this analysis shows association rather than direction, both KLF17-to-partner and partner-to-KLF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of focal adhesion assembly grouped by KLF17-low versus KLF17-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF17→partner) and Y-score (partner→KLF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of focal adhesion assembly →	+0.174	+0.642	<.001	.006	3	11
BONE	Regulation of cell-substrate junction assembly →	+0.174	+0.642	<.001	.006	3	11
BONE	Positive regulation of actin filament bundle assembly →	+0.247	+0.835	<.001	.003	3	9
BONE	Regulation of cell-substrate junction organization →	+0.166	+0.642	<.001	.006	3	9
BONE	Positive regulation of cell-substrate junction organization →	+0.198	+0.643	<.001	.006	3	9
BONE	Regulation of cell-matrix adhesion →	+0.160	+0.640	<.001	.006	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,131 associations by consensus.

Regulation of focal adhesion assembly by KLF17 expression — BONE

Explore this box plot interactively →