KLF17

Across TCGA cell cohorts, KLF17 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLF17-associated genes across cancer lineages are CLLU1-AS1, CFAP97D2, and FAM71C. Each is linked with KLF17 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF17-to-partner and partner-to-KLF17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLLU1-AS1 grouped by KLF17-low versus KLF17-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF17→partner) and Y-score (partner→KLF17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	CLLU1-AS1 →	+0.113	+5.087	<.001	.004	3	1
URINARY_TRACT	CFAP97D2 →	+0.043	+5.087	<.001	.004	3	1
SKIN	FAM71C →	+0.018	+5.095	<.001	<.001	3	1
BLOOD_Lymphoma	PABPC1L2A →	+0.033	+5.643	<.001	.002	3	1
LARGE_INTESTINE	G6PC2 →	+0.038	+4.099	<.001	.001	3	1
LARGE_INTESTINE	PRSS48 →	+0.067	+3.714	.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

CLLU1-AS1 by KLF17 expression — URINARY_TRACT

Explore this box plot interactively →