KLF13

Across TCGA patient cohorts, KLF13 mutation is significantly associated with the RNA expression of many other genes, with 2,427 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KLF13-associated genes across cancer lineages are RN7SL248P, RNU6-1214P, and MIR7-3. Each is linked with KLF13 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLF13-to-partner and partner-to-KLF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by KLF13-low versus KLF13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF13→partner) and Y-score (partner→KLF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.054	+3.059	<.001	.005	3	3
CESC	RNU6-1214P →	+0.355	+5.306	<.001	.006	3	1
CESC	MIR7-3 →	+0.370	+6.342	<.001	.001	3	1
CESC	DNMT3AP1 →	+0.030	+5.418	<.001	.005	3	1
CESC	FAM245A →	+0.119	+5.418	<.001	.005	3	1
CESC	VN1R4 →	+0.043	+5.812	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,427 associations by consensus.

RN7SL248P by KLF13 expression — UCEC

Explore this box plot interactively →