KLC4

Across TCGA patient cohorts, KLC4 protein abundance is significantly associated with the RNA expression of many other genes, with 16,908 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible KLC4-associated genes across cancer lineages are OARD1, YIPF3, and SLC5A9. Each is linked with KLC4 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLC4-to-partner and partner-to-KLC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLC4 versus OARD1 in LSCC, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLC4→partner) and Y-score (partner→KLC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	OARD1 →	+0.521	+0.248	<.001	<.001	3	6
HNSC	YIPF3 →	+0.543	+0.250	.001	<.001	3	6
CCRCC	SLC5A9 →	+1.012	+0.351	<.001	<.001	3	6
HNSC	ILDR1 →	+1.083	+0.246	<.001	<.001	3	6
CCRCC	REPS2 →	+1.071	+0.229	<.001	.003	3	6
CCRCC	AMIGO1 →	+1.268	+0.344	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,908 associations by consensus.

KLC4 vs OARD1 — LSCC

Explore this scatter interactively →