KISS1R

Across TCGA patient cohorts, KISS1R protein abundance is significantly associated with the RNA expression of many other genes, with 161 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KISS1R-associated genes across cancer lineages are ISM2, GATA1, and DGKH. Each is linked with KISS1R in more than 1 cancer types. Because this analysis shows association rather than direction, both KISS1R-to-partner and partner-to-KISS1R results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KISS1R versus ISM2 in UCEC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KISS1R→partner) and Y-score (partner→KISS1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ISM2 →	+0.633	+0.345	.007	.007	3	1
UCEC	GATA1 →	+0.510	+0.293	.001	.002	3	1
UCEC	DGKH →	-1.628	-0.426	.008	.007	3	1
UCEC	WNT3 →	+0.702	+0.293	<.001	.001	3	1
UCEC	SLC4A3 →	+2.119	+0.371	<.001	.003	3	1
UCEC	DOCK7 →	+0.529	+0.260	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 161 associations by consensus.

KISS1R vs ISM2 — UCEC

Explore this scatter interactively →