KISS1R

Across TCGA cell cohorts, KISS1R RNA expression is significantly associated with the go_rna of many other GO terms, with 1,422 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KISS1R-associated GO terms across cancer lineages are Proton motive force-driven ATP synthesis, Proton motive force-driven mitochondrial ATP synthesis, and Oxidative phosphorylation. Each is linked with KISS1R in more than 7 cancer types. Because this analysis shows association rather than direction, both KISS1R-to-partner and partner-to-KISS1R results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proton motive force-driven ATP synthesis grouped by KISS1R-low versus KISS1R-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KISS1R→partner) and Y-score (partner→KISS1R) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Proton motive force-driven ATP synthesis →	+0.091	+1.545	<.001	<.001	3	8
LUNG_SCLC	Proton motive force-driven mitochondrial ATP synthesis →	+0.088	+1.545	<.001	<.001	3	7
LUNG_SCLC	Oxidative phosphorylation →	+0.083	+1.296	<.001	<.001	3	7
LUNG_SCLC	Aerobic respiration →	+0.088	+1.516	.002	<.001	3	7
LUNG_SCLC	Purine nucleoside triphosphate biosynthetic process →	+0.082	+1.604	<.001	<.001	3	7
LUNG_SCLC	Purine ribonucleoside triphosphate biosynthetic process →	+0.082	+1.604	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,422 associations by consensus.

Proton motive force-driven ATP synthesis by KISS1R expression — LUNG_SCLC

Explore this box plot interactively →