KIR3DL3

Across TCGA cell cohorts, KIR3DL3 RNA expression is significantly associated with the RNA expression of many other genes, with 748 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible KIR3DL3-associated genes across cancer lineages are KIR2DL3, PRAMEF18, and FAM71B. Each is linked with KIR3DL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIR3DL3-to-partner and partner-to-KIR3DL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIR3DL3 versus KIR2DL3 in BLOOD_Lymphoma, with a Pearson correlation of 0.71.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIR3DL3→partner) and Y-score (partner→KIR3DL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	KIR2DL3 →	+1.367	+0.101	<.001	.008	3	5
UPPER_AERODIGESTIVE_TRACT	PRAMEF18 →	+0.139	+0.029	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	FAM71B →	+0.023	+0.029	<.001	<.001	3	4
UPPER_AERODIGESTIVE_TRACT	SPATA31A7 →	+0.168	+0.017	<.001	<.001	3	3
UPPER_AERODIGESTIVE_TRACT	OR8D4 →	+0.069	+0.029	<.001	<.001	3	3
CNS	OR1L4 →	+0.146	+0.042	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 748 associations by consensus.

KIR3DL3 vs KIR2DL3 — BLOOD_Lymphoma

Explore this scatter interactively →