KIF5B

Across TCGA patient cohorts, KIF5B mutation is significantly associated with the RNA expression of many other genes, with 4,324 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF5B-associated genes across cancer lineages are MIR8053, KCTD9, and BCAS2. Each is linked with KIF5B in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF5B-to-partner and partner-to-KIF5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR8053 grouped by KIF5B-low versus KIF5B-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF5B→partner) and Y-score (partner→KIF5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR8053 →	+0.287	+4.342	<.001	.007	3	3
UCEC	KCTD9 →	+0.702	+2.010	<.001	<.001	3	3
UCEC	BCAS2 →	+0.403	+2.917	.002	<.001	3	3
UCEC	PINK1-AS →	+0.399	+2.098	<.001	.002	3	3
UCEC	GCH1 →	+0.756	+2.032	<.001	<.001	3	3
UCEC	GTF2A2 →	+0.375	+1.776	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,324 associations by consensus.

MIR8053 by KIF5B expression — CESC

Explore this box plot interactively →