KIF4A

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, KIF4A protein abundance is significantly associated with the RNA expression of many other genes, with 17,546 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF4A-associated genes across cancer lineages are CENPI, PKMYT1, and TCF19. Each is linked with KIF4A in more than 7 cancer types. Because this analysis shows association rather than direction, both KIF4A-to-partner and partner-to-KIF4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF4A versus CENPI in LUAD, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF4A→partner) and Y-score (partner→KIF4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADCENPI →+1.377+0.839<.001<.00138
UCECPKMYT1 →+1.209+0.762<.001<.00138
HNSCTCF19 →+1.251+0.431<.001<.00138
BRCAPOLA2 →+0.611+0.691<.001<.00138
COADERCC6L →+1.226+0.751<.001.00238
UCECMCM5 →+1.294+0.986<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,546 associations by consensus.

KIF4A vs CENPI — LUAD

Per-sample scatter of KIF4A vs CENPI in LUAD (Pearson r = 0.72).

Explore this scatter interactively →

Exploration